The cytokinetic cleavage furrow must be carefully aligned with the spindle midzone during asymmetric cell division. Pacquelet et al. (http://ow.ly/SQAoM) discover a pathway that maintains the connection between spindle and furrow position in one-cell C. elegans embryos by inhibiting the accumulation of myosin at the anterior cortex during cytokinesis. Here from first author Anne Pacquelet in the latest biosights video below: | Journal of Cell Biology
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