Rapid reviews are a type of evidence synthesis that summarise findings from different research studies by accelerating the ...

Aligning research funding and the production of useful evidence to reduce research waste (1 December, 2025) ...

Background Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic ...

Introduction: High-quality randomised controlled trials (RCTs) provide the most reliable evidence on the comparative efficacy of new medicines. However, non-randomised studies (NRS) are increasingly ...

Correspondence to Professor J. David Spence, Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, ON, N6G 2V4, Canada; dspence{at}robarts.ca ...

We have evaluated dietary recommendations for people diagnosed with familial hypercholesterolaemia (FH), a genetic condition in which increased low-density lipoprotein cholesterol (LDL-C) is ...

This paper forms part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group and addresses rapid qualitative evidence syntheses (QESs), which use modified systematic, ...

Correspondence to Professor Kari A O Tikkinen, Department of Urology, Helsinki University Hospital, Helsinki 00290, Finland; kari.tikkinen{at}helsinki.fi To practice high quality healthcare, ...

Background Musculoskeletal knee pain is a large and costly problem, and meniscal tears make up a large proportion of diagnoses. ‘Special tests’ to diagnose torn menisci are often used in the physical ...

Correspondence to Dr Mohammad Hassan Murad, Evidence-Based Practice Center, Mayo Clinic, Rochester, MN 55905, USA; murad.mohammad{at}mayo.edu In 1904, Dr James Herrick evaluated a 20-year-old patient ...

Generative artificial intelligence (AI) moved from an experimental novelty into mainstream use as an everyday tool in under 3 years. Large language models (LLMs) now pass portions of knowledge ...