Brandon Aiyuk hasn't been a part of the San Francisco 49ers' season, and Kyle Shanahan opened up with his regret amid the ...

As the San Francisco 49ers prepare for a crucial Week 16 'Monday Night Football' showdown against the Indianapolis Colts, safety Malik Mustapha is hitting ...

Although 49ers receiver Ricky Pearsall reinjured the knee that kept him out of six games earlier this season, coach Kyle ...

The San Francisco 49ers are preparing for their Week 16 contest against the Indianapolis Colts on Monday night at Lucas Oil ...

San Francisco 49ers TE George Kittle, RB Christian McCaffrey, and DL Keion White discussed the energy inside the locker room, ...

The San Francisco 49ers might have a new face at linebacker when they visit the Indianapolis Colts in Week 16.

San Francisco 49ers head coach Kyle Shanahan highlighted Indianapolis' run defense, reflected on overcoming injuries, and ...

Kyle Shanahan says wide receiver Brandon Aiyuk has been 'extremely distant' since his ACL/MCL injuries last season.

Brandon Aiyuk has not played this season after suffering a torn ACL and MCL in Week 7 of the 2024 campaign, and San Francisco ...

The San Francisco 49ers have a big Week 16 Monday Night Football clash against the Colts, and here are bold predictions.

The 49ers defeated the Titans on Sunday, and 49ers head coach Kyle Shanahan was mic'd up for the matchup, which happened to ...