During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary. Now, researchers from Japan demonstrate that aromatic ...

Prostate cancer is one of the most common malignancies in men globally. Hormonal therapies targeting the androgen–androgen ...

Research led by the Department of General and Visceral Surgery, Faculty of Medicine, University of Freiburg, Germany has ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

Using a newly discovered byproduct of dying cancer cells, University of Wisconsin–Madison researchers are developing personalized vaccines that could help keep aggressive tumors from recurring.

Treating types of cancer with CAR T-cell therapy is expensive and inconvenient, but a streamlined approach that creates the therapy within the body could make the intervention cheaper and easier ...

Diet-based intervention The study used a mouse model designed to mimic pancreatic cancer development. The mice were fed either a high-fat diet or a low-fat diet for 21 weeks. A third group was fed a ...

Methods: A syngeneic breast cancer model was established in 6-week-old C57BL/6 mice by subcutaneous injection of 4T1-luciferase tumor cells. The mice were divided into six groups (control, 0.5 Gy, 1 ...

In three different mouse models of ER+ breast cancers, the researchers found that a single dose of ErSO-TFPy was enough to either nearly or completely eradicate tumors across a whole range of sizes.

In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

Scientists in Texas have created the world's first mouse model with a fully functional human immune system. By Inno Flores Updated: Jul 08 2024, 04:08 AM EDT ...

This study aims to elucidate CASTOR1’s role in a transgenic Kras-driven LUAD mouse model, shedding light on its tumor-suppressive potential. Methods: Utilizing a novel CASTOR1 knockout (KO) mouse ...