The 49ers released their final injury report for the regular season opener against the Los Angeles Rams following yesterday's ...

The San Francisco 49ers secured a 27-7 win over the Los Angeles Rams in their historic Week 1 matchup at the Melbourne ...

San Francisco 49ers QB Brock Purdy, WR Mike Evans, TE George Kittle, LB Dre Greenlaw, WR Deebo Samuel Sr., RB Christian ...

San Francisco 49ers head coach Kyle Shanahan provided injury updates for WR De'Zhaun Stribling, TE Jake Tonges, and others, ...

San Francisco 49ers K Eddy Piñeiro's 56-yard field goal extends the 49ers lead to 27-7 in the Week 1 matchup vs. the Los ...

Catch up on the latest San Francisco 49ers headlines, powered by Cisco.

San Francisco 49ers QB Brock Purdy's best throws from his 3-TD game in Melbourne against the Los Angeles Rams during Week 1 ...

Broadcast and streaming information for the San Francisco 49ers Week 1 matchup against the Los Angeles Rams at Melbourne ...

Take a look at players who have been ruled out for the San Francisco 49ers Week 1 matchup versus the Los Angeles Rams.

The San Francisco 49ers released their latest injury updates headed into the season opener contest against the Los Angeles Rams.

Watch the best plays by the San Francisco 49ers against the Los Angeles Rams in Week 1 of the 2026 NFL season.

San Francisco 49ers WR Demarcus Robinson scores a 39-yard touchdown in the Week 1 matchup vs. the Los Angeles Rams.