Objective This study aimed to compare 25-hydroxyvitamin D (25-(OH)D) levels and peripheral lymphocyte subsets between ...
Objectives DNASE1L3 deficiency is a rare monogenic cause of early-onset SLE and hypocomplementaemic urticarial vasculitis ...
The case for early biologic therapy in systemic lupus erythematosus (SLE) is intuitively appealing but requires closer scrutiny. First, ‘early’ is poorly defined with UK survey data showing a mean ...
Background The short-term and long-term outcome of inflammatory neuropsychiatric SLE (NPSLE) with immunosuppressive treatment is largely unknown. We used clinical data from our tertiary referral ...
Systemic lupus erythematosus (SLE) is a profoundly heterogeneous disease in which clinical phenotype emerges from the interplay of autoantibody profiles, organ involvement, cytokine signatures, ...
Case 1: A 43-year-old Caucasian woman with fever, acute tonsillitis, nausea and diarrhoea A 43-year-old Caucasian woman with SLE was admitted at the Hospital Clínic of Barcelona with fever, acute ...
Objectives Cardiovascular disease is a leading cause of morbidity and mortality in systemic lupus erythematosus (SLE), largely driven by endothelial dysfunction. Belimumab, a monoclonal antibody ...
Objective To characterise the safety and efficacy of anifrolumab in active lupus nephritis (LN) through year 2 of the phase II randomised, double-blind Treatment of Uncontrolled Lupus via the ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
Haematologic involvement in patients with systemic lupus erythematosus (SLE) is very common. The principal cytopenias in lupus result in anaemia, white cell deficits and thrombocytopenia. Anaemia may ...
Fumaric acid esters in cutaneous lupus erythematosus Fumaric acid esters (FAEs), established immunomodulatory agents in the treatment of psoriasis and multiple sclerosis, have been investigated for ...
Case 1: A 35-year-old female with SLE and planning IVF pregnancy In October 2024 a 35-year-old female with systemic lupus erythematosus (SLE) was reviewed for planning of in vitro fertilization (IVF) ...