Introduction: High-quality randomised controlled trials (RCTs) provide the most reliable evidence on the comparative efficacy of new medicines. However, non-randomised studies (NRS) are increasingly ...

BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and ...

Aligning research funding and the production of useful evidence to reduce research waste (1 December, 2025) ...

Correspondence to Professor J. David Spence, Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, ON, N6G 2V4, Canada; dspence{at}robarts.ca ...

We have evaluated dietary recommendations for people diagnosed with familial hypercholesterolaemia (FH), a genetic condition in which increased low-density lipoprotein cholesterol (LDL-C) is ...

Background Antibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic ...

This paper forms part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group and addresses rapid qualitative evidence syntheses (QESs), which use modified systematic, ...

Rapid reviews are a type of evidence synthesis that summarise findings from different research studies by accelerating the ...

Toward automating GRADE classification: a proof-of-concept evaluation of an artificial intelligence-based tool for semiautomated evidence quality rating in systematic reviews ...

Correspondence to Matt Oxman, Faculty of Health Sciences, Oslo Metropolitan University, Oslo NO-0130, Norway; matt{at}mattoxman.com Healthcare students and professionals, as well as patients and ...

Correspondence to Professor Kari A O Tikkinen, Department of Urology, Helsinki University Hospital, Helsinki 00290, Finland; kari.tikkinen{at}helsinki.fi To practice high quality healthcare, ...