Researchers have achieved a clean reversal of Type 1 diabetes in mice by rebuilding their immune systems and restoring ...

The U.S. Food and Drug Administration approved an Investigational New Drug (IND) application using efficacy data solely from ...

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, ...

Sickle cell disease is associated with chronic oxidative stress, hemolysis, inflammation, and progressive multi--organ injury, including significant cardiopulmonary complications. Mitochondrial ...

The companies plan to test the treatment's efficacy in preclinical models of squamous cell lung carcinoma early next year.

A new nanoparticle vaccine successfully prevented several aggressive cancers in mice, including pancreatic and melanoma. The ...

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy. Despite advances in ...

A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide ...

PSA is a validated FDA-recognized clinical endpoint in assessing prostate cancer treatment response; Telomir-1 lowered PSA ...

Two teams discover how small cell lung cancer hijacks neural pathways to proliferate faster, especially to the brain. Common ...

Following guidance from the FDA prioritizing preclinical alternatives to mouse models, some academic and community cancer centers are setting up organoid cores.