A 46-year-old man with CKD presented with a 2-year history of painless shortening and rounding of the fingertips. Radiographs of the hands showed resorption of the terminal tufts of all the distal ...

Patients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral ...

Nonobstructive hypertrophic cardiomyopathy (HCM) is a common condition that is associated with substantial morbidity and no ...

Pulmonary hypertension that is caused by left heart disease and is associated with heart failure may be driven by sympathetic ...

The effectiveness and safety of statins for the primary prevention of cardiovascular events and the extension of disability-free survival among older adults remain uncertain. We conducted a ...

Whether catheter-directed thrombolysis improves clinical outcomes in patients with intermediate-high–risk pulmonary embolism, ...

Atherosclerosis may begin in early adulthood and remain clinically silent for decades before cardiovascular disease manifests. Although silent atherosclerosis is associated with cardiovascular ...

The effect of clopidogrel monotherapy as compared with extended dual antiplatelet therapy (DAPT) with clopidogrel and aspirin ...

Approximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery ...

This editorial describes the science behind a study of mezigdomide, which augments the degradation of the proteins Ikaros and Aiolos, to treat multiple myeloma.

Stroke is a severe and common complication of atrial fibrillation. Anticoagulation with vitamin K antagonists or with direct oral anticoagulants (DOACs) prevents the majority of strokes in ...

A 44-year-old man presented with a 4-year history of choking episodes while eating. Endoscopy revealed narrowing of the upper esophagus by a pulsating, cordlike structure in the posterior wall (sho ...