Iron is well-known as an inducer of ferroptosis–a type of cell death triggered by iron-mediated lipid peroxidation. Despite its role in ferroptosis, an iron overload-induced ferroptosis animal model ...
Transmembrane serine protease 6 (TMPRSS6) is a negative regulator of hepcidin, which is the main iron homeostasis-regulating hormone. Regeneron Pharmaceuticals Inc. has recently presented preclinical ...
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Living well with hemochromatosis and iron overload
What it is: Hemochromatosis is a genetic or acquired condition causing excess iron storage, which can damage the heart, liver, pancreas, and other organs over time. Why it matters: Untreated iron ...
Study reveals liraglutide's potential to regulate iron metabolism and improve glucose tolerance in a mouse model of hereditary hemochromatosis and obesity. Study: Liraglutide Impacts Iron Homeostasis ...
Multi-echo T2* MRI identifies neonatal haemochromatosis through thyroid and pancreatic iron patterns in neonatal liver ...
Subscribe to our newsletter for the latest sci-tech news updates. Excess intracellular iron triggers the production of highly reactive oxygen species, which rapidly oxidize phospholipids, causing cell ...
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