“This is a wonderful piece of work,” said Henrik Zetterberg at the University of Gothenburg, Sweden. He was not involved in the research. “It now seems possible to use [plasma p-tau217] to track the ...

Unlike other prior studies that detected changes in AD markers following COVID-19 infection ( Jan 2021 news; May 2023 conference news ), first author Duff and colleagues had baseline data on every ...

Scientists are urgently seeking fluid biomarkers for frontotemporal dementia, the most common dementing illness among 40- and ...

In related news, other scientists recently reported that phospho-tau isoforms in the CSF mirror protofibrillar forms of tau, ...

At the Human Amyloid Imaging (HAI) meeting, held January 15-17, researchers focused on new techniques—all based on tau and ...

When it comes to tau tangles, cortical deposits receive the lion’s share of scientists’ attention, but it is the tiny subcortical regions where tangles originate that might set the course for ...

Detecting toxic forms of tau before they weave into dense thickets of tangles could pave the way for earlier diagnosis and ...

Although efforts to identify biomarkers for Alzheimer's disease are advancing rapidly, many still struggle to obtain information from populations other than non-Hispanic white people. At the Human ...

In Alzheimer’s disease, microglia pack on fat, which impairs phagocytosis. Now, scientists led by Christiane Ruedl of Nanyang Technological University, Singapore, report that blocking lipid buildup in ...

Synaptic dysfunction heralds cognitive and behavioral decline in neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases. Oligomers of Aβ, tau, and ɑ-synuclein may be to blame, but ...