Ritter‐type reactions represent a cornerstone of amide bond construction through the interception of carbocationic intermediates with nitriles. Traditionally catalysed by strong acids or Lewis acids, ...
With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...
Highly reactive organometallic reagents, like organolithiums (molecules with a carbon–lithium bond) are essential reagents in organic synthesis because of their applications from polymer synthesis to ...
The synthesis of materials can serve as a tool for developing smart, adaptive electrocatalysts. This rapidly evolving field ...
Figure 1. LoRA-Chem: From Model Customization to Organic Chemistry Reaction Tasks. (a) Several machine learning algorithm paradigms applied to organic chemistry. (b) Inspired by AI-driven image style ...
Merck researchers developed a highly sustainable way to synthesize the macrocyclic peptide drug enlicitide, increasing ...
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