Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...
The development of advanced sequencing technologies has made it easier to obtain diverse templates for specific targets, such as nucleotide sequences in NCBI 1, 16S ribosomal RNA gene sequences in ...
Sequence alignment is an essential component of bioinformatics, for identifying regions of similarity that may indicate functional, structural, or evolutionary relationships between the sequences.
Three papers in this issue of present major advances in understanding the evolution of birds and mammals, made possible by new methods for comparing the genomes of hundreds of species. Three papers ...
The LAGAN Alignment Toolkit consists of three online alignment tools. Pairwise-LAGAN allows users to perform global alignments of two sequences; Multi-LAGAN performs global alignment of up to 31 ...
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