According to the World Health Organization, 422 million adults across the globe have diabetes. To help the growing patient population, researchers are going down to the molecular level. Here, they're ...

A high serum proinsulin level and a low insulin-like-growth-factor-binding protein 1 (IGFBP-1) level are predictors of cardiovascular disease and diabetes in obese adults, but little evidence exists ...

Could cow milk be the new cure for diabetes? Researchers have genetically modified a brown cow in Brazil to produce human insulin in its milk, which marks a breakthrough in diabetes treatment research ...

Proinsulin-transferrin (ProINS-Tf) fusion protein was evaluated for its in vivo pharmacokinetics, efficacy, and mechanism. Our previous studies have shown that ProINS-Tf was converted to active ...

In a recent study published in the Biotechnology Journal, a team of researchers from Brazil constructed a lentivirus vector with expression specific for mammary glands and carrying the gene for human ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 16 (Aug. 6, 2002), pp. 10299-10304 (6 pages) The neuroendocrine processing endoproteases PC2 and PC1/3 are ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

A genetically modified cow has produced milk containing human insulin, according to a new study. The proof-of-concept achievement could be scaled up to, eventually, produce enough insulin to ensure ...

THE protein hormone insulin seems to be of perennial interest to biochemists. It was among the first to be crystallized and was the first protein whose primary structure was elucidated by Sanger and ...

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...

ANN ARBOR, Mich. - According to the World Health Organization, 422 million adults across the globe have diabetes. In fact, the number of adults with the disease continues to grow each year. To help ...