"If it ain't broke, don't fix it," goes the old adage, which Rice University professor James Chappell completely ignored in a recent Nature Communications publication. In the study, Chappell describes ...
From the Bedalov Lab, Translational Science and Therapeutics and Human Biology Divisions When I asked Foss and Bedalov whether the known replication origins in yeast shared any sequence-level features ...
DNA replication in eukaryotic cells is a highly coordinated, multi-step process that ensures precise duplication of the genome prior to cell division. In late mitosis and early G1 phase, the Origin ...
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Uncovering the principle by which DNA replication initiation sites are determined in the human genome
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...
Every time a cell divides, it must copy roughly three billion letters of DNA with near-perfect fidelity. That copying process, DNA replication, is among the most demanding operations a cell performs, ...
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