Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease, both ...
Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study by a team at the Max Planck Institute ...
Taken together, our experimental paradigm in endothelial cells and VSMCs indicates that under normal conditions insulin is antiatherogenic. In endothelial cells, insulin stimulates NO production and ...