LocalGov

Government urged to stop reorganisation or face 'massive car crash'

Government should be told to stop Local Government Reorganisation (LGR) or face a ‘massive car crash' a county leader facing ...
Business Insider

Carina Biotech Doses First Patient in Phase 1/2a Clinical Trial of LGR5-Targeted CAR-T Cell Therapy

First patient dosed in Australia where 3 clinical trial sites have been activated. The trial will enrol advanced colorectal cancer patients whose cancer expresses the cancer stem cell marker LGR5, and ...
WDAF-TV

Carina Biotech to Present Details of Planned Phase 1/2a Clinical Trial of LGR5-Targeted CAR-T Cell Therapy Candidate CNA3103 for Metastatic Colorectal Cancer at 2023 ASCO ...

First in human, multicenter, open label, Phase 1/2a dose escalation and expansion study to determine the safety of and overall best response to CNA3103 in subjects with mCRC Phase 1 segment of the ...
WDTN

Carina Biotech to Present Preclinical Data Evaluating LGR5-Targeted CAR-T Cell Therapy in Human Cancer Models at 8th CAR-TCR Summit

LGR5 is expressed, both in vitro and in vivo, by numerous human cancers, including colorectal, ovarian, gastric, brain, and pancreatic cancer. LGR5-targeting CAR-T cells effectively kill ...
WAVY-TV

Carina Biotech to Present Preclinical Data at Lorne Cancer 2023 Supporting Effectiveness of LGR5-Targeted CAR-T Cell Therapy Platform in Ovarian Cancer Tumor Models

Preclinical evidence shows that LGR5 targeted CAR-T cells are able to kill ovarian cancer cells and to reduce ovarian cancer tumor burden in animal models The data suggests that LGR5 CAR-T cells have ...