Hydroxyurea is an oral chemotherapy drug that doctors may prescribe to people with sickle cell disease. It may help prevent complications due to sickle-shaped blood cells clumping together in small ...

Hydroxyurea remains effective over the long term among children with sickle cell disease, real-world data suggested. The average time on hydroxyurea was 5 years, with many children on the therapy for ...

Hydroxyurea is generally contraindicated in patients with sickle cell disease who become or plan to become pregnant, but post-marketing safety data suggest that treatment continuation is safe. The ...

Prolonged treatment with hydroxyurea may improve -- and possibly even reverse -- cardiac complications in pediatric patients with sickle cell anemia, a retrospective study found. Those on hydroxyurea ...

Fewer ED visits per year and fewer hospital days per year seen in association with hydroxyurea use. HealthDay News — For children with sickle cell anemia (SCA), hydroxyurea has sustained clinical ...

Machine learning identified RDW and HGB as key predictors of hydroxyurea resistance in polycythemia vera, aiding early identification and treatment adjustment. The PV-AIM study used electronic health ...

Please provide your email address to receive an email when new articles are posted on . Three-quarters of women who became pregnant during hydroxyurea therapy had live births. Researchers observed no ...

Please provide your email address to receive an email when new articles are posted on . Use of hydroxyurea did not reduce ovarian reserve among girls and young women with sickle cell disease.

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in patients with hemoglobin SC, a milder form of sickle cell disease (SCD), a ...

Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving ...

The discovery that hydroxyurea interferes with the functioning of the Dexcom G6 continuous glucose monitor (CGM) in patients with diabetes came about from communication between one patient and one ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...