Self-DNA triggers cGAS-STING-mediated type I interferon (IFN-I) to induce both protective and pathogenic immune responses; however, how self-DNA activates the cytosolic cGAS-STING pathway remains ...
Fluorescence microscopy illustrates immune cell–mediated extraction of nuclear DNA from dying cells, highlighting a newly identified process called nucleocytosis. Over the years, cell biology has ...
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