Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with ...

St. Louis, Feb. 18, 2009 — Each year in the United States, doctors start about 2 million patients on warfarin (Coumadin™), an anticoagulant drug that's notoriously hard to administer. Now a study from ...

Seattle, WA - Researchers in Seattle say they have uncovered specific genetic variations that influence how people respond to warfarin dose. Their study suggests that haplotypes of the VKORC1 gene can ...

In a large-scale study and an upcoming clinical trial, scientists supported by the National Institutes of Health address one of the trickiest issues in prescribing medicine—how to quickly optimize ...

Daily warfarin dosing requirements clearly decrease with advancing age. To examine the relation between age and warfarin dosing, researchers analyzed data from 101 U.S. sites that were participating ...

Patients with HIV received a mean warfarin dose of 6.20 mg/day. Results showed that mean induction times, analyzed in 170 patients, were 12.87 days in the HIV-infected patients and 11.19 days in the ...